Medical Diagnosis Laboratory:
The Medical Diagnosis Laboratory of Royan Institute is one of the chief laboratories among infertility laboratories. It has specialized subdivisions for sperm analysis, andrology, hormonology, immunology and biochemistry.
Our deepest purpose as the leading laboratory is establishing a monitoring and evaluation mechanism for performance of Ministry of Health and Medical Education in regard to health laboratory services. On one hand, to reach the aim, Medical Diagnosis Laboratory of Royan Institute specifies its quality management system based on ISO 9001:2008 and the international standard for medical laboratories ISO 15189 associated with spermogram. On the other hand, the Laboratory proposes high levels of efficiency and quality in services to patients and beneficiaries by help of skillful and expert health professionals.
Vision
The main goal of Medical Diagnosis Laboratory of Royan Institute is to turn this laboratory into a foremost, exemplary, fast and influential organization among all infertility laboratories in Iran.
Various Laboratory Subdivisions at Royan Institute:
Electrophoresis, Immunology, Sperm Analysis, Biochemistry and Serology, Pathology, Blood Sampling, Flow Cytometry, Coronavirus (covid-19), Molecular Diagnostic Laboratory, Microbiology, Sperm Sampling, Hematology, Hormonology and Screening.
Laboratory of Molecular Genetics and PGT:
Laboratory of Molecular Genetics and PGT of Royan Institute is dedicated to providing unparalleled genetic testing services through expertise, commitment to research and development, and investment in the latest technologies.
The services cover the following:
- Pre-implantation genetic testing for monogenic disorders (PGT-M), a laboratory procedure used in conjunction with in vitro fertilization (IVF) to reduce the risk of passing on inherited conditions such as: minor beta thalassemia
- The QF-PCR technique has the advantage of providing rapid results for the diagnosis or exclusion of aneuploidy in chromosomes 13, 18, 21, X or Y. I
- Detection of microdeletions of the long arm of the Y chromosome in infertile men.
- Assessment of mutations in the Connexin 26 and 30 genes and mitochondrial mutation for diagnosis of genetic deafness.
- Evaluate of thrombophilia factors like II, V, PAI-1, XIII, and MTHFR for diagnosis of hereditary cases in patients with recurrent abortion or recurrent implantation failure.
- Using the FMR1 test for screening the cases of CGG repeat expansion in patients with premature ovarian failure (POF).
- Investigating and diagnosing of common mutations in beta-thalassemia and alpha-thalassemia genes under the title of first-stage PND.
- Confirmation of mutations in beta-thalassemia and alpha-thalassemia genes on fetal samples (CVS or amnion) under the title of second-stage PND.
- Genetic diagnosis of Spinal Muscular Atrophy (SMA).
- Confirmation of mutations reported by WES method for other family members under the title of Mutation Confirmation.
- Evaluation of FSHR and LHCGR polymorphisms for diagnosis of gentic etiologies of poor ovarian response to FSH hormone.
- Preimplantation genetic testing (PGT), a screening test that can be performed on embryos created via in vitro fertilization (IVF) to genetically analyze the embryos prior to transfer. PGT-A (testing embryo for aneuploidy) can ensure that the embryo selected for transfer has the correct number of chromosomes, thereby reducing the chances for a failed IVF cycle and reducing the chance of miscarriage.
- The NIPT, a safe and highly effective way of screening for chromosomal abnormalities in fetus that include:
- Down syndrome (trisomy 21)
- Edwards syndrome (trisomy 18)
- Patau syndrome (trisomy 13)
- Turner syndrome (monosomy of X) and other sex chromosomal aneuploidies