In embryology, cleavage is the division of cells in the early development of the embryo, following fertilization. The zygotes of many species undergo rapid cell cycles with no significant overall growth, producing a cluster of cells the same size as the original zygote.
IVF-created embryos generally are transferred into the uterus at either the cleavage stage or blastocyst stage. Usually, embryos contain of 4 cells on day 2 and 8 cells on day 3.